Childbirth anxiety causes changes in a woman's mind during the third trimester. Prolonged worry can make it difficult for pregnant women to focus and cause them to lose confidence. Purpose: This study determines the relationship between self-efficacy and anxiety levels of third-trimester primigravida pregnant women. Methods: This study used crosssectional data and correlation analysis. The purposive sampling method selected 82 thirdtrimester pregnant women as the study population. The study sample included 57 thirdtrimester pregnant women per the inclusion criteria. This study used two questionnaires: the self-confidence scale and the Revised Pregnancy-Related Anxiety Questionnaire (PRAQ-R2). The research results on self-efficacy obtained 63.2% with moderate self-efficacy, while anxiety levels obtained the majority with moderate anxiety at 49.1%. Data analysis using the Spearman Rank correlation test formula obtained a correlation coefficient of 0.645 with a significance of 0.000 (p <0, 05). Conclusion: There is a significant relationship in the self-efficacy of thirdtrimester primigravida pregnant women with anxiety levels with a strong correlation coefficient.